Atypical fibroxanthoma management: Recurrence, metastasis and disease-specific death Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun-damaged skin, with no evidence-based guidelines for their management.
and metastasis. Discussion Atypical fibroxanthoma (AFX) is typically a diagnosis of exclusion that requires histopathologic and immunohistochemical analysis to distinguish it from tumors with similar clinical and microscopic appearances. Histopathologically, AFX appears extremely abnormal, with a dermal proliferation of
Metastatic carcinoma : Background. Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic Atypical fibroxanthoma is a skin cancer often seen in sun-exposed areas. It resembles squamous cell carcinoma or basal cell carcinoma because of the presence of a pink papule or erosion. It is usually diagnosed only after biopsy. Tumors involving the dermis and superficial fat are termed atypical fibroxanthoma and rarely metastasize.
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head and neck) of elderly patients with a slight male predominance. Histologically, a dermal based, well circumscribed tumor composed of pleomorphic, irregularly arranged, spindled to epithelioid cells with numerous mitotic figures. Metastatic Atypical Fibroxanthoma: Case Report of an Uncommon Pathology in the Head and Neck Introduction Atypical fibroxanthoma (AFX) is a rare skin malignancy generally developed in elderly male patients with actinic damage. Due to its low rate of metastasis, it is considered a benign neoplasm [1,2]. BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. Metastatic disease has been reported very rarely.
Atypical fibroxanthoma with regional lymph node metastasis: report of a case and review of the literature. Arch Dermatol. 2010;146(12):1399–404. PubMed CrossRef Google Scholar
Metastatic disease has been reported very rarely. The potential aggressiveness of AFX is controversial.
Home > April 15, 2003 - Volume 111 - Issue 5 > ATYPICAL FIBROXANTHOMA AND METASTASIS TO THE LUNG. Log in to view full text. If you're not a subscriber, you can:
Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that typically has low-grade malignant potential. Although recurrences do occur, only approximately 25 cases of metastasizing AFX have been reported. Herein a patient with an AFX that metastasized and eventuated in death is described.
Atypical Fibroxanthoma of the Scalp With Cutaneous Metastasis. Ryan, Michael P. BS *; Nguyen, Adam V. MD
Atypical fibroxanthoma management: Recurrence, metastasis and disease-specific death Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun-damaged skin, with no evidence-based guidelines for their management. Atypical fibroxanthoma (AFX) is a dermal mesenchymal neoplasm arising in sun-damaged skin, primarily of the head and neck region of older men.
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Metastatic carcinoma: Should be considered in the differential diagnosis for patients with a known history of carcinoma Lesional cells are usually positive for pancytokeratin and other immunohistochemical markers similar to the primary tumor Superficial CD34+ fibroblastic tumor: May overlap with histologic variants of atypical fibroxanthoma Atypical fibroxanthoma management: Recurrence, metastasis and disease-specific death Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun-damaged skin, with no evidence-based guidelines for their management. 2015-06-09 BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. Metastatic disease has been reported very rarely. The potential aggressiveness of AFX is controversial.
What are the clinical features of atypical fibroxanthoma? A solitary tumour or multiple tumours may occur. Typically, AFX is a red, juicy, dome-shaped nodule that may be bleeding, ulcerated or crusted.
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Jun 30, 2020 of atypical fibroxanthoma as genetic modifications are concurrent and metastasis from intrinsic, visceral malignancies [6,7]. Spindle cell
Background: Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. Abstract. Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that typically has low-grade malignant potential.
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BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. Metastatic disease has been reported very rarely. The potential aggressiveness of AFX is controversial. OBSERVATIONS: We describe herein a patient who developed metastatic disease in cervical lymph nodes.
Atypical fibroxanthoma (AFX) Jul 13, 2018 Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma the risk of recurrence or metastasis, and irradiation poses the risk of causing Feb 3, 2010 Kligora C.J.; Goldstein G.D.. Localized cutaneous metastases from an atypical fibroxanthoma. Dermatol Surg. 2004; 30: 1561- Aug 16, 2016 Here's my sample pathology report template for AFX vs pleomorphic dermal sarcoma: https://kikoxp.com/posts/5193. A complete organized An Atypical Fibroxanthoma (AFX) is an uncommon type of skin cancer, accounting for less than 0.2 % of all skin cancers.